Ilfracombe trailed twice away to Melksham before coming through to snatch victory 3-2 in the closing minutes.
Billy Tucker was their hero of the hour when he latched on to a cross from Steve Copp to knock home the winner with four minutes remaining.
Combe fell behind after 25 minutes when Melksham’s Gary Higdon headed home from a corner.
But they took the game to their visitors and a well-worked one-two between Steve Holland and Ed Yeo ended with Holland scoring his first goal of the season to bring them level at the break.
The second half started with chances for both sides before Melksham took the lead again when Tom Drewitt punished a defensive mistake.
But Combe maintained their pace and were rewaded with a great strike from Kevin Darch - also his first goal of the campaign - to put them back on terms again just seven minutes later.
They continued to create the better chances, with both Copp and Shaun Lewis going close before Tucket grabbed the deserved winner.
Ilfracombe were entertaining Buckland Athletic last night (Tuesday) before a Saturday clash away to Hallen.
Barnstaple could not recreate the efforts of their notable midweek draw with Willand as they slumped to a 4-1 defeat at the hands of Bristol Manor Farm.
“It was as if we had a hang-over from that game. We looked tired,” said manager Dave Griffiths.
Town made it more difficult by conceding a goal in the opening three minutes to Ricky Chandler after early pressure by the home team.
But all did not then seem lost as Exeter loanee Jamie Micklewight picked up a ball put through from the back by Liam Dart to produce a great solo effort for an equaliser midway through the opening half.
A good four-man move saw Barnstaple press again, but Mitch Cisineros just failed to get on the end of it.
The Manor Farm dominated. They scored a second goal by Leigh Edwards-Samuels just before the interval and shortly after a shot by Ashley Knight was parried by diving keeper Darren Rose only to rebound back to the attacker to knock home.
Two minutes from time and Chandler hit Manor’s fourth for a result which leaves Town propping up the division.
Town have a tough task at home to title contenders Bitton on Saturday.